The 5 Triggers of Inflammation: What They Are and How to Address Them

To some extent, we need inflammation in the body. (For example, an acute response to stop the bleeding if you cut yourself.)

However, when inflammation goes unchecked, and the body keeps mounting an inflammatory response to the same trigger, it leads to chronic inflammation and disease. 

Integrative medicine teaches us that we need to look at not only why the body is responding to a trigger but also at what that trigger is.

A concept I discuss in-depth in my book, Healthy Kids, Happy Moms, is the five main triggers of inflammation.

As you can see from the graphic above, it’s the interaction of our genes with these triggers that determines our overall health. 

Our bodies don’t have fences, so inflammatory cells can travel anywhere in the body, from the gut to the brain to the skin.

Therefore, poorly controlled asthma is related to constipation and stomach aches. Recurrent ear infections are related to uncontrolled eczema.

This also applies to our nervous system. Have you ever noticed your child’s behavior is worse if he or she has gone three or four days without a bowel movement? Or, at the height of allergy season, does he or she seem more irritable? If a child has tics, I often see them worsen during allergy season.

In short, all these triggers interplay with one another, and one symptom may exacerbate another. It’s all connected!

To illustrate this point, let’s look at Gary’s case study from chapter 2 of my book.

The Symptoms of Inflammation

Gary was four years old when his mother brought him to see me. He had a persistent cough for several months, and throughout the previous two years, he had recurrent bouts of coughing, running nose, and wheezing that required an albuterol inhaler.

He had taken one course of oral steroids for the wheezing that caused his behavior to become erratic, with irritability, mood swings, and sleep troubles.

Fortunately, his mother’s intuition was telling her that his symptoms were being caused by an underlying issue not being addressed. 

During his office visit, I observed that he was an audible mouth breather (what I affectionately refer to as “Darth Vader breathing”), he had a runny nose, and dark, puffy circles under his eyes. 

On exam, I noticed the inside of his nose (nasal mucosa) was pale in color and swollen, a tell-tale sign of environmental allergies. 

The Triggers of Inflammation

We have a saying in medicine, “If you ask the right questions, the patient will tell you what’s wrong.” 

Gary was sleeping on a fifteen-year-old mattress from his uncle’s college days. We knew he had a highly significant dust mite allergy due to blood work from his previous pediatrician. 

Gary also had signs and symptoms of inflammation classic for someone with a dairy sensitivity.
He had two out of the five inflammatory triggers–environmental allergies (dust mites) and food (dairy).

The Outcome of Resolving Inflammation

Gary improved rapidly, and to this day, he is doing great. At his follow-up appointment three weeks later, Gary’s chronic nasal congestion and cough had almost completely resolved

Eventually, so did the dark circles under his eyes and the mouth breathing. His need for albuterol also decreased.

He is one of the hundreds of children I have seen over the years who were statistically more likely to progress to asthma. Using the best of both conventional and integrative medicine, we decrease their exposure to the particular triggers of inflammation, and the kids experience an improved trajectory of their health. 

If you are noticing an uptick in your child’s symptoms this allergy season, my team and I would love to help your family get to the root cause of inflammation!

Share

Recent Posts

Benedryl and Dementia

Benadryl and Dementia: What You Need to Know

Most of us don’t think twice about giving our child Benadryl for allergies, congestion, or even sleep—but new research is raising red flags for long-term use. A 2025 Harvard study linked long-term use...
Read More
Child sneezing inside from the dust and poor indoor air quality

Indoor Air Quality: Tips To Allergy Proof Your Home

Did you know that indoor air quality can be up to five times more polluted than outdoor air? Mind blowing, right?! If your child struggles with allergies, we want to...
Read More
Allergy testing can be done via Skin Prick Test or Blood Testing

Eczema and Asthma: Why Allergy Testing Is So Important

Did you know 50-80% of kids with eczema and asthma also have environmental allergies? So doesn’t it make sense to do some allergy testing to identify what they’re allergic to...
Read More

What If You Could Break Your Child's Sick Cycle?

Discover 7 Steps to Heal and
Prevent Common Childhood Illnesses

Online Course

The Healthy Kids, Happy Moms Companion Course is a physician-led, parent-centered, time-tested online course that includes assessments, workbooks, recipes, and illness-specific recommendations.

Become a Patient

 Dr. Kilbane’s private practice, Infinite Health, is based in Charlotte, North Carolina. She is currently accepting new patients

What If You Could Break Your Child's Sick Cycle?

Discover 7 Steps to Heal and
Prevent Common Childhood Illnesses

Online Course

The Healthy Kids, Happy Moms Companion Course is a physician-led, parent-centered, time-tested online course that includes assessments, workbooks, recipes, and illness-specific recommendations.

Become a Patient

 Dr. Kilbane’s private practice, Infinite Health, is based in Charlotte, North Carolina. She is currently accepting new patients

Join the Practitioner Training Wait List!

Privacy Policy: We hate spam and promise to keep your email address safe.

What You Get With The Eczema Jump Start Guide:

Dr. Kilbane’s approach is universal and can be used by both children and adults who have eczema. Here’s what’s included: